The journal has been published annually since 1999 by the Polish Academy of Arts and Sciences.
From 1999 to 2007, it had been published under the title Prace Komisji Historii Nauki Polskiej Akademii Umiejętności (Proceedings of the Commission on the History of Science of the Polish Academy of Arts and Sciences), then from 2009 to 2015 – under the title Prace Komisji Historii Nauki PAU (Proceedings of the PAU Commission on the History of Science).
Until 2012 it had been published in a printed (paper) form, and since 2013 it has been published in an electronic form and in print (paper).
In 2014, the journal became the first in Poland peer-reviewed open access journal devoted to the history of science. Since that year it has been issued under the Creative Commons license.
Under the court decision of the Sąd Okręgowy w Krakowie Wydział I Cywilny, reference number Sygn. akt Ns Rej. Pr. 115/16 of July 4, 2016, the name of the journal was changed to: Studia Historiae Scientiarum.
The historical predecessor of this journal were Prace Komisji Medycyny i Nauk Matematyczno-Przyrodniczych Polskiej Akademii Umiejętności (Proceedings of the Commission of the History of Medicine and Mathematical and Natural Sciences of the Polish Academy of Arts and Sciences), which were irregularly published in 1939 (vol. 1), 1949 (vols. 2, 3.1, 3.2), 1950 (vol. 3.3), 1952 (vols 4.1, 4.2) and 1953 (vol. 4.3) [published after the activity of the Academy had been suspended].